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Nivelul reziduurilor de oxitetraciclina in ouale gainilor dupa administrarea orala a medicamentului in apa de baut pentru stabilirea puilor.

Omija B, Mitema ES, Maitho TE.
Department of Public Health, Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Nairobi, Kenya.

     S-a experimentat pe un numar de 20 de pasari care au fost divizate in 4 grupuri (n=5) si care au primit dozele de 0, 400, 600 şi 800 mg/l oxitetraciclina in apa de baut timp de 7 zile. Ouale au fost colectate timp de 17 zile dupa administrarea medicamentului si au fost depozitate la 4oC. Reziduurile de oxitetraciclina in galbenus si albus au fost analizate folosind metoda microbiologica cu Bacillus cereus var. mycoides ATCC 11778. Concentratia medie maxima de oxitetraciclina s-a observat cu 2 zile mai tarziu in albus si apoi in galbenus. Valoarea medie a galbenusului si a albusului a fost 0.526 si respective 0.280 mg/kg. Perioada de depletie a fost mai scurta pentru albus apoi pentru galbenus, iar oxitetraciclina a fost detectata in galbenius si albus dupa 13 respectiv 10 zile. Intreruperea tratamentului depinde de concentratia antibioticului administrat. Reziduurile de oxitetraciclina ating rapid un peak in albus apoi in galbenus, desi reziduurile persista o perioada lunga de timp.

Food Addit Contam. 1994 Nov-Dec;11(6):641-7.


Oxytetracycline residue levels in chicken eggs after oral administration of medicated drinking water to laying chickens.

Omija B, Mitema ES, Maitho TE.
Department of Public Health, Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Nairobi, Kenya.

     Twenty laying birds were divided into four groups (n = 5) and given drinking water containing 0, 400, 600, and 800 mg/l of oxytetracycline respectively for 7 days. Eggs were collected continuously for 17 days after drug administration and stored at +4 degrees C. The oxytetracycline residues in yolk and albumen were analysed using a microbiological method with Bacillus cereus var. mycoides ATCC 11778 as the test organism. The mean maximum concentration of oxytetracycline was observed 2 days earlier in the albumen than in the yolk. The mean values in yolk and albumen were 0.526 and 0.280 mg/kg respectively. The depletion period was shorter for albumen than for yolk and oxytetracycline was detected in the yolk and albumen up to days 13 and 10 respectively. Withdrawal periods depended on the concentration of the antibiotic administered. Oxytetracycline residues reached a peak faster in albumen than in yolk, although the residues persisted for longer periods in the yolk.

Food Addit Contam. 1994 Nov-Dec;11(6):641-7


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